How common is misinformation about COVID-19 on social media?

Bottom Line: Misinformation concerning the COVID-19 pandemic is prevalent on social media, and can have serious public health implications. Reference: Islam, M. S et al. COVID-19–related Infodemic and its impact on public health: A global social media analysis. The American Journal of Tropical Medicine and Hygiene (2020). Date Published: 10 August 2020 Synopsis: A lot of misinformation about [...]

How easily is SARS-CoV-2 transmitted in educational settings?

Bottom Line: Educational settings might not contribute significantly to the spread of COVID-19 when there are effective contact-tracing measures and smaller class sizes. Reference: Macartney, K. et al. Transmission of SARS-CoV-2 in Australian educational settings: a prospective cohort study. The Lancet (2020). Date Published: 3 August 2020 Synopsis: The COVID-19 pandemic has caused many [...]

What is the risk of transmitting COVID-19 to newborns?

Bottom Line: The risk of transmission of COVID-19 from mothers to newborns is low when proper masking and hand hygiene is practiced. Reference: Salvatore, C. et al. Neonatal management and outcomes during the COVID-19 pandemic: An observation cohort study. The Lancet Child & Adolescent Health (2020). Date Published: 23 July 2020 Synopsis: The risk of a newborn [...]

What were the characteristics of nursing homes in the U.S. that reported cases of COVID-19?

Bottom Line: While nursing homes that reported COVID-19 cases had similar overall ratings to those that did not, nursing homes that reported COVID-19 did have a higher average of reported incidents and complaints. Reference: Chatterjee, P. et al. Characteristics and quality of US nursing homes reporting cases of coronavirus disease 2019 (COVID-19). JAMA Network Open (2020). Date [...]

How does COVID-19 affect the central nervous system with regards to speech and language?

Bottom Line: The COVID-19 disease may be associated with unusual speech distortions leading to foreign accent syndrome. Reference: Cotelli, M. S. et al. Effortful speech with distortion of prosody following SARS-Cov-2 infection. Neurological Sciences (2020). Date Published: 19 July 2020 Synopsis: The COVID-19 infection has been reported to target the central nervous system, leading to the manifestations [...]

What are the clinical outcomes and side effects in COVID-19 patients treated with off-label hydroxychloroquine and azithromycin?

Bottom Line: The clinical benefits of hydroxychloroquine and azithromycin combination therapy were minimal and were associated with a significant increase in toxicity. Reference: Kelly, M. et al. Clinical outcomes and adverse events in patients hospitalised with COVID ‐19, treated with off‐ label hydroxychloroquine and azithromycin. British Journal of Clinical Pharmacology (2020). Date Published: 20 July 2020 Synopsis: [...]

What are the preferences of Ontario patients and healthcare providers regarding ‘virtual healthcare’ visits?

Bottom Line: Virtual healthcare visits - visits that do not involve a face-to-face meeting between the patient and provider - are perceived as high-quality by Ontario patients, and both patients and healthcare providers prefer message-based visits over phone or video visits. Reference: Stamenova V. et al. Uptake and patient and provider communication modality preferences of [...]

What were the results from the first published study on a COVID-19 vaccine?

Bottom Line: Preliminary data shows that the mRNA-1273 vaccine generates immune response to SARS-COV2 without serious adverse effects, thereby supporting further development of this vaccine. Reference: Jackson L.A. et al. An mRNA Vaccine against SARS-CoV-2 - Preliminary Report. N Engl J Med (2020). Date Published: 16 July 2020 Synopsis: Many clinical trials for vaccine development [...]

Which symptoms were persistent in individuals who recovered from COVID-19?

Bottom Line: Individuals who had recovered from COVID-19 exhibited persistent symptoms including fatigue, shortness of breath, chest pain and joint pain. Only 12% of patients were completely symptom-free. Reference: Carfì A. Persistent Symptoms in Patients After Acute COVID-19. JAMA (2020). DOI: 10.1001/jama.2020.12603 Date Published: 9 July 2020 Synopsis: One of the many questions regarding the trajectory [...]